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TitleA Stably Protonated Adenine Nucleotide with a Highly Shifted pKa Value Stabilizes the Tertiary Structure of a GTP-Binding RNA Aptamer.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 56, Page 401-404, Year 2017
Publish dateSep 17, 2016 (structure data deposition date)
AuthorsWolter, A.C. / Weickhmann, A.K. / Nasiri, A.H. / Hantke, K. / Ohlenschlager, O. / Wunderlich, C.H. / Kreutz, C. / Duchardt-Ferner, E. / Wohnert, J.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:27885761
MethodsNMR (solution)
Structure data

PDB-5lwj:
Solution NMR structure of the GTP binding Class II RNA aptamer-ligand-complex containing a protonated adenine nucleotide with a highly shifted pKa.
Method: SOLUTION NMR

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

Source
  • synthetic construct (others)
KeywordsRNA / RNA structure / aptamer / protonated adenine / GTP

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