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-Structure paper
Title | The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity. |
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Journal, issue, pages | Sci Transl Med, Vol. 8, Page 365ra159-365ra159, Year 2016 |
Publish date | Aug 10, 2016 (structure data deposition date) |
Authors | Wieczorek, M. / Tcherkezian, J. / Bernier, C. / Prota, A.E. / Chaaban, S. / Rolland, Y. / Godbout, C. / Hancock, M.A. / Arezzo, J.C. / Ocal, O. ...Wieczorek, M. / Tcherkezian, J. / Bernier, C. / Prota, A.E. / Chaaban, S. / Rolland, Y. / Godbout, C. / Hancock, M.A. / Arezzo, J.C. / Ocal, O. / Rocha, C. / Olieric, N. / Hall, A. / Ding, H. / Bramoulle, A. / Annis, M.G. / Zogopoulos, G. / Harran, P.G. / Wilkie, T.M. / Brekken, R.A. / Siegel, P.M. / Steinmetz, M.O. / Shore, G.C. / Brouhard, G.J. / Roulston, A. |
External links | Sci Transl Med / PubMed:27856798 |
Methods | X-ray diffraction |
Resolution | 2.4 Å |
Structure data | PDB-5lov: |
Chemicals | ChemComp-GTP: ChemComp-MG: ChemComp-CA: ChemComp-GDP: ChemComp-MES: ChemComp-71E: ChemComp-ACP: ChemComp-HOH: |
Source |
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Keywords | CELL CYCLE / TUBULIN FOLD / CYTOSKELETON / MICROTUBULE |