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TitleStructural Basis of N-Myc Binding by Aurora-A and its Destabilization by Kinase Inhibitors
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 113, Page 13726-, Year 2016
Publish dateMar 31, 2016 (structure data deposition date)
AuthorsRichards, M. / Burgess, S. / Poon, E. / Carstensen, A. / Eilers, M. / Chesler, L. / Bayliss, R.
External linksProc. Natl. Acad. Sci. USA / PubMed:27837025
MethodsX-ray diffraction
Resolution1.72 Å
Structure data

PDB-5g1x:
Crystal structure of Aurora-A kinase in complex with N-Myc
Method: X-RAY DIFFRACTION / Resolution: 1.72 Å

Chemicals

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / AURORA / AURORA-A / KINASE / N-MYC / MYC / NEUROBLASTOMA

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