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-Structure paper
Title | Structure-guided design of purine-based probes for selective Nek2 inhibition. |
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Journal, issue, pages | Oncotarget, Vol. 8, Page 19089-19124, Year 2017 |
Publish date | Oct 20, 2016 (structure data deposition date) |
![]() | Coxon, C.R. / Wong, C. / Bayliss, R. / Boxall, K. / Carr, K.H. / Fry, A.M. / Hardcastle, I.R. / Matheson, C.J. / Newell, D.R. / Sivaprakasam, M. ...Coxon, C.R. / Wong, C. / Bayliss, R. / Boxall, K. / Carr, K.H. / Fry, A.M. / Hardcastle, I.R. / Matheson, C.J. / Newell, D.R. / Sivaprakasam, M. / Thomas, H. / Turner, D. / Yeoh, S. / Wang, L.Z. / Griffin, R.J. / Golding, B.T. / Cano, C. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.899 - 2.4 Å |
Structure data | ![]() PDB-5m51: ![]() PDB-5m53: ![]() PDB-5m55: ![]() PDB-5m57: |
Chemicals | ![]() ChemComp-NU6: ![]() ChemComp-HOH: ![]() ChemComp-7GJ: ![]() ChemComp-PEG: ![]() ChemComp-EDO: ![]() ChemComp-PO4: ![]() ChemComp-7GG: ![]() ChemComp-SO4: ![]() ChemComp-CL: ![]() ChemComp-4SP: |
Source |
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![]() | Transferase/Inhibitor / Protein kinase / Inhibitor / Centrosome separation / Transferase-Inhibitor complex / TRANSFERASE |