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Structure paper

TitleMHC class II complexes sample intermediate states along the peptide exchange pathway.
Journal, issue, pagesNat Commun, Vol. 7, Page 13224-13224, Year 2016
Publish dateDec 6, 2014 (structure data deposition date)
AuthorsWieczorek, M. / Sticht, J. / Stolzenberg, S. / Gunther, S. / Wehmeyer, C. / El Habre, Z. / Alvaro-Benito, M. / Noe, F. / Freund, C.
External linksNat Commun / PubMed:27827392
MethodsX-ray diffraction
Resolution1.34 - 3.199 Å
Structure data

PDB-4x5w:
HLA-DR1 with CLIP102-120(M107W)
Method: X-RAY DIFFRACTION / Resolution: 1.34 Å

PDB-4x5x:
HLA-DR1 mutant bN82A with covalently linked CLIP106-120(M107W)
Method: X-RAY DIFFRACTION / Resolution: 3.199 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / MHC II / SELF ANTIGEN / INVARIANT CHAIN / CLIP

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