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-Structure paper
Title | Development of a high-throughput crystal structure-determination platform for JAK1 using a novel metal-chelator soaking system. |
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Journal, issue, pages | Acta Crystallogr F Struct Biol Commun, Vol. 72, Page 840-845, Year 2016 |
Publish date | Jun 16, 2016 (structure data deposition date) |
Authors | Caspers, N.L. / Han, S. / Rajamohan, F. / Hoth, L.R. / Geoghegan, K.F. / Subashi, T.A. / Vazquez, M.L. / Kaila, N. / Cronin, C.N. / Johnson, E. / Kurumbail, R.G. |
External links | Acta Crystallogr F Struct Biol Commun / PubMed:27827355 |
Methods | X-ray diffraction |
Resolution | 2.4 - 2.47 Å |
Structure data | PDB-5khw: PDB-5khx: |
Chemicals | ChemComp-ADP: ChemComp-MG: ChemComp-HOH: ChemComp-6TE: |
Source |
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Keywords | TRANSFERASE / JAK1 / Kinase / Inhibitor / Complex / transferase/transferase INHIBITOR / transferase-transferase INHIBITOR complex |