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TitleDifferences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors.
Journal, issue, pagesCell Rep, Vol. 17, Page 1560-1570, Year 2016
Publish dateSep 23, 2016 (structure data deposition date)
AuthorsYacoob, C. / Pancera, M. / Vigdorovich, V. / Oliver, B.G. / Glenn, J.A. / Feng, J. / Sather, D.N. / McGuire, A.T. / Stamatatos, L.
External linksCell Rep / PubMed:27806295
MethodsX-ray diffraction
Resolution1.858 - 2.741 Å
Structure data

PDB-5tf1:
Structure of chimeric 02-CC Fab, a VRC01-like germline antibody
Method: X-RAY DIFFRACTION / Resolution: 1.858 Å

PDB-5tfs:
Structure of chimeric 02-K Fab, a VRC01-like germline antibody
Method: X-RAY DIFFRACTION / Resolution: 2.319 Å

PDB-5tgb:
Structure of chimeric 02-CB Fab, a VRC01-like germline antibody
Method: X-RAY DIFFRACTION / Resolution: 2.741 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Fab / germline / VRC01-like / CD4-BS / HIV-1 / CDRH3 / VRC01 / Vh1-2

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