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Structure paper

TitleStructural elements of an NRPS cyclization domain and its intermodule docking domain.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 113, Page 12432-12437, Year 2016
Publish dateSep 6, 2016 (structure data deposition date)
AuthorsDowling, D.P. / Kung, Y. / Croft, A.K. / Taghizadeh, K. / Kelly, W.L. / Walsh, C.T. / Drennan, C.L.
External linksProc. Natl. Acad. Sci. USA / PubMed:27791103
MethodsX-ray diffraction
Resolution2.03 - 2.604 Å
Structure data

PDB-5t7z:
Monoclinic crystal form of the EpoB NRPS cyclization-docking bidomain from Sorangium cellulosum
Method: X-RAY DIFFRACTION / Resolution: 2.03 Å

PDB-5t81:
Rhombohedral crystal form of the EpoB NRPS cyclization-docking bidomain from Sorangium cellulosum
Method: X-RAY DIFFRACTION / Resolution: 2.604 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • sorangium cellulosum (bacteria)
KeywordsBIOSYNTHETIC PROTEIN / epothilone / NRPS / thiazoline / cyclization

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