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TitleLessons from the Crystal Structure of the S. aureus Surface Protein Clumping Factor A in Complex With Tefibazumab, an Inhibiting Monoclonal Antibody.
Journal, issue, pagesEBioMedicine, Vol. 13, Page 328-338, Year 2016
Publish dateMay 4, 2016 (structure data deposition date)
AuthorsGanesh, V.K. / Liang, X. / Geoghegan, J.A. / Cohen, A.L. / Venugopalan, N. / Foster, T.J. / Hook, M.
External linksEBioMedicine / PubMed:27789272
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-5jq6:
Crystal structure of ClfA in complex with the Fab fragment of Tefibazumab
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • staphylococcus aureus (bacteria)
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Staphylococcal infections / Clumping factor A / Fibrinogen / Tefibazumab / Aurexis / MSCRAMM

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