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Structure paper

TitleStructure of the essential Haemophilus influenzae UDP-diacylglucosamine pyrophosphohydrolase LpxH in lipid A biosynthesis.
Journal, issue, pagesNat Microbiol, Vol. 1, Page 16154-16154, Year 2016
Publish dateMay 30, 2016 (structure data deposition date)
AuthorsCho, J. / Lee, C.J. / Zhao, J. / Young, H.E. / Zhou, P.
External linksNat Microbiol / PubMed:27780190
MethodsX-ray diffraction
Resolution2.55 Å
Structure data

PDB-5k8k:
Structure of the Haemophilus influenzae LpxH-lipid X complex
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-LP5:
(R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE

ChemComp-ACT:
ACETATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd) (bacteria)
KeywordsHYDROLASE / LpxH / lipid X / UDP-diacylglucosamine / lipid A / LPS / lipopolysaccharide / antibiotic / calcineurin-like phosphoesterase

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