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Structure paper

TitleHuman CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors.
Journal, issue, pagesProtein Sci., Vol. 26, Page 242-257, Year 2017
Publish dateAug 11, 2016 (structure data deposition date)
AuthorsClark, K.M. / Jenkins, J.L. / Fedoriw, N. / Dumont, M.E.
External linksProtein Sci. / PubMed:27774687
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-5syt:
Crystal Structure of ZMPSTE24
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-PC1:
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE / phospholipid*YM

ChemComp-CXE:
PENTAETHYLENE GLYCOL MONODECYL ETHER

ChemComp-C8E:
(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE / C8E, detergent*YM

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / MEMBRANE PROTEIN / CaaX protease / zinc metalloprotease / STE24 / isoprenylation / Structural Genomics / PSI-2 / Protein Structure Initiative / Membrane Protein Structural Biology Consortium / MPSBC

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