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Title8-Oxoguanine Affects DNA Backbone Conformation in the EcoRI Recognition Site and Inhibits Its Cleavage by the Enzyme.
Journal, issue, pagesPlos One, Vol. 11, Page e0164424-e0164424, Year 2016
Publish dateMar 18, 2016 (structure data deposition date)
AuthorsHoppins, J.J. / Gruber, D.R. / Miears, H.L. / Kiryutin, A.S. / Kasymov, R.D. / Petrova, D.V. / Endutkin, A.V. / Popov, A.V. / Yurkovskaya, A.V. / Fedechkin, S.O. ...Hoppins, J.J. / Gruber, D.R. / Miears, H.L. / Kiryutin, A.S. / Kasymov, R.D. / Petrova, D.V. / Endutkin, A.V. / Popov, A.V. / Yurkovskaya, A.V. / Fedechkin, S.O. / Brockerman, J.A. / Zharkov, D.O. / Smirnov, S.L.
External linksPlos One / PubMed:27749894
MethodsNMR (solution)
Structure data

PDB-5iv1:
Solution Structure of DNA Dodecamer with 8-oxoguanine at 4th Position
Method: SOLUTION NMR

PDB-5izp:
Solution Structure of DNA Dodecamer with 8-oxoguanine at 10th Position
Method: SOLUTION NMR

Source
  • synthetic construct (others)
KeywordsDNA / Drew-Dickerson / dodecamer / non-canonical / modified DNA / oxidized DNA / DNA damage / DNA adduct / lesion

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