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Structure paper

TitleStructural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 138, Page 15035-15045, Year 2016
Publish dateOct 20, 2015 (structure data deposition date)
AuthorsNagy, G.N. / Suardiaz, R. / Lopata, A. / Ozohanics, O. / Vekey, K. / Brooks, B.R. / Leveles, I. / Toth, J. / Vertessy, B.G. / Rosta, E.
External linksJ. Am. Chem. Soc. / PubMed:27740761
MethodsX-ray diffraction
Resolution1.3 - 1.97 Å
Structure data

PDB-5ect:
Mycobacterium tuberculosis dUTPase G143STOP mutant
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-5edd:
Crystal structure of Mycobacterium tuberculosis dUTPase R140K, H145W mutant
Method: X-RAY DIFFRACTION / Resolution: 1.97 Å

Chemicals

ChemComp-DUP:
2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-MG:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsHYDROLASE / JELLY-ROLL / TRIMER / ENZYME-LIGAND COMPLEX

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