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TitleTunable Probes with Direct Fluorescence Signals for the Constitutive and Immunoproteasome.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 55, Page 13330-13334, Year 2016
Publish dateJun 14, 2016 (structure data deposition date)
AuthorsDubiella, C. / Cui, H. / Groll, M.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:27709817
MethodsX-ray diffraction
Resolution2.5 - 2.9 Å
Structure data

PDB-5lai:
Ligand-induced aziridine-formation at the yeast proteasomal subunit beta5 by sulfonate esters
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-5laj:
Ligand-induced Lys33-Thr1 crosslinking at the yeast proteasomal subunit beta5 by sulfonate esters
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-3K4:
(2S,3S)-3-methylaziridine-2-carboxylic acid

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (strain atcc 204508 / s288c) (yeast)
KeywordsHYDROLASE / Proteasome / Fluorescent Probes / Binding Analysis / Umpolung / Crosslink

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