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TitlePalonosetron-5-HT3 Receptor Interactions As Shown by a Binding Protein Cocrystal Structure.
Journal, issue, pagesACS Chem Neurosci, Vol. 7, Page 1641-1646, Year 2016
Publish dateSep 20, 2016 (structure data deposition date)
AuthorsPrice, K.L. / Lillestol, R.K. / Ulens, C. / Lummis, S.C.
External linksACS Chem Neurosci / PubMed:27656911
MethodsX-ray diffraction
Resolution2.34 Å
Structure data

PDB-5lxb:
Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with palonosetron
Method: X-RAY DIFFRACTION / Resolution: 2.34 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-7A9:
palonosetron / medication, chemotherapy, antagonist*YM

ChemComp-HOH:
WATER

Source
  • aplysia californica (California sea hare)
Keywordsacetylcholine binding protein / Cys-loop receptor / 5-HT3 receptor

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