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TitleBinding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 113, Page 11202-11207, Year 2016
Publish dateJun 21, 2016 (structure data deposition date)
AuthorsKvansakul, M. / Lay, F.T. / Adda, C.G. / Veneer, P.K. / Baxter, A.A. / Phan, T.K. / Poon, I.K. / Hulett, M.D.
External linksProc. Natl. Acad. Sci. USA / PubMed:27647905
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-5kk4:
Crystal Structure of the Plant Defensin NsD7 bound to Phosphatidic Acid
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-SO4:
SULFATE ION

ChemComp-ACT:
ACETATE ION

ChemComp-44E:
(2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate / phospholipid*YM

ChemComp-HOH:
WATER

Source
  • nicotiana suaveolens x nicotiana tabacum (plant)
KeywordsANTIMICROBIAL PROTEIN / defensin / phospholipid / oligomer / phosphatidic acid

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