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Structure paper

TitleMolecular basis of a novel renal amyloidosis due to N184K gelsolin variant.
Journal, issue, pagesSci Rep, Vol. 6, Page 33463-33463, Year 2016
Publish dateDec 11, 2015 (structure data deposition date)
AuthorsBoni, F. / Milani, M. / Porcari, R. / Barbiroli, A. / Ricagno, S. / de Rosa, M.
External linksSci Rep / PubMed:27633054
MethodsX-ray diffraction
Resolution1.05 - 1.7 Å
Structure data

PDB-5fae:
N184K pathological variant of gelsolin domain 2 (trigonal form)
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-5faf:
N184K pathological variant of gelsolin domain 2 (orthorhombic form)
Method: X-RAY DIFFRACTION / Resolution: 1.05 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-ACT:
ACETATE ION

Source
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / gelsolin / amyloidosis / calcium / mutation / actin

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