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Structure paper

TitleStructural insights into the molecular mechanism of the m(6)A writer complex.
Journal, issue, pagesElife, Vol. 5, Year 2016
Publish dateMay 29, 2016 (structure data deposition date)
AuthorsSledz, P. / Jinek, M.
External linksElife / PubMed:27627798
MethodsX-ray diffraction
Resolution1.852 - 1.901 Å
Structure data

PDB-5l6d:
Crystal structure of the human METTL3-METTL14 complex bound to SAH
Method: X-RAY DIFFRACTION / Resolution: 1.852 Å

PDB-5l6e:
Crystal structure of the human METTL3-METTL14 complex bound to SAM
Method: X-RAY DIFFRACTION / Resolution: 1.901 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-MG:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-SAM:
S-ADENOSYLMETHIONINE

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / RNA methyltransferase N6-adenine methylation Rossmann fold / methyltransferase N6-adenine methylation m6A Rossmann fold

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