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Structure paper

TitleDelta chirality ruthenium 'light-switch' complexes can bind in the minor groove of DNA with five different binding modes.
Journal, issue, pagesNucleic Acids Res., Vol. 44, Page 9472-9482, Year 2016
Publish dateApr 19, 2016 (structure data deposition date)
AuthorsHall, J.P. / Keane, P.M. / Beer, H. / Buchner, K. / Winter, G. / Sorensen, T.L. / Cardin, D.J. / Brazier, J.A. / Cardin, C.J.
External linksNucleic Acids Res. / PubMed:27599841
MethodsX-ray diffraction
Resolution0.97 - 0.99 Å
Structure data

PDB-5jeu:
del-[Ru(phen)2(dppz)]2+ bound to d(TCGGCGCCGA) with Ba2+
Method: X-RAY DIFFRACTION / Resolution: 0.97 Å

PDB-5jev:
del-[Ru(phen)2(dppz]2+ bound to d(TCGGCGCCGA) with Cobalt hexammine
Method: X-RAY DIFFRACTION / Resolution: 0.99 Å

Chemicals

ChemComp-BA:
Unknown entry

ChemComp-0TN:
Delta-Ru(phen)2(dppz) complex

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-NCO:
COBALT HEXAMMINE(III)

Source
  • synthetic construct (others)
KeywordsDNA / ruthenium / light-switch / semi-intercalation / cross-linking / DNA probe

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