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Structure paper

TitleDistinctive Klf4 mutants determine preference for DNA methylation status.
Journal, issue, pagesNucleic Acids Res., Vol. 44, Page 10177-10185, Year 2016
Publish dateJun 9, 2016 (structure data deposition date)
AuthorsHashimoto, H. / Wang, D. / Steves, A.N. / Jin, P. / Blumenthal, R.M. / Zhang, X. / Cheng, X.
External linksNucleic Acids Res. / PubMed:27596594
MethodsX-ray diffraction
Resolution1.99 - 2.458 Å
Structure data

PDB-5ke6:
mouse Klf4 ZnF1-3 and TpG/CpA sequence DNA complex structure
Method: X-RAY DIFFRACTION / Resolution: 1.99 Å

PDB-5ke7:
mouse Klf4 ZnF1-3 and TpG/MpA sequence DNA complex structure
Method: X-RAY DIFFRACTION / Resolution: 2.06 Å

PDB-5ke8:
mouse Klf4 E446P ZnF1-3 and MpG/MpG sequence DNA complex structure
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

PDB-5ke9:
mouse Klf4 E446P ZnF1-3 and TpG/CpA sequence DNA complex structure
Method: X-RAY DIFFRACTION / Resolution: 2.336 Å

PDB-5kea:
mouse Klf4 ZnF1-3 (E446D) and CpG/CpG sequence DNA complex structure: Form I
Method: X-RAY DIFFRACTION / Resolution: 2.458 Å

PDB-5keb:
mouse Klf4 ZnF1-3 (E446D) and CpG/CpG sequence DNA complex structure: Form II
Method: X-RAY DIFFRACTION / Resolution: 2.453 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • mus musculus (house mouse)
  • synthetic construct (others)
Keywordstranscription/DNA / klf4 / zinc finger / Kruppel-like factors / transcription-DNA complex / transcription factor/DNA / transcription factor-DNA complex / unmethylated cytosine specific

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