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TitleStructural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles.
Journal, issue, pagesCell Chem Biol, Vol. 23, Page 1103-1112, Year 2016
Publish dateMay 22, 2015 (structure data deposition date)
AuthorsAleem, S.U. / Georghiou, G. / Kleiner, R.E. / Guja, K.E. / Craddock, B.P. / Lyczek, A. / Chan, A.I. / Garcia-Diaz, M. / Miller, W.T. / Liu, D.R. / Seeliger, M.A.
External linksCell Chem Biol / PubMed:27593110
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-5bmm:
Src in complex with DNA-templated macrocyclic inhibitor MC25b
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
  • synthetic construct (others)
KeywordsTransferase/transferase Inhibitor / Transferase-transferase Inhibitor complex

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