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Structure paper

TitleThe Structure of the Antibiotic Deactivating, N-hydroxylating Rifampicin Monooxygenase.
Journal, issue, pagesJ. Biol. Chem., Vol. 291, Page 21553-21562, Year 2016
Publish dateJul 1, 2016 (structure data deposition date)
AuthorsLiu, L.K. / Abdelwahab, H. / Martin Del Campo, J.S. / Mehra-Chaudhary, R. / Sobrado, P. / Tanner, J.J.
External linksJ. Biol. Chem. / PubMed:27557658
MethodsX-ray diffraction
Resolution1.8 - 2.1 Å
Structure data

PDB-5kow:
Structure of rifampicin monooxygenase
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-5kox:
Structure of rifampicin monooxygenase complexed with rifampicin
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-RFP:
RIFAMPICIN / antibiotic*YM

Source
  • nocardia farcinica (bacteria)
KeywordsOXIDOREDUCTASE / flavoprotein / monooxygenase

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