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| Title | Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype. |
|---|---|
| Journal, issue, pages | J. Biol. Chem., Vol. 291, Page 20487-20502, Year 2016 |
| Publish date | Nov 6, 2015 (structure data deposition date) |
Authors | McCammon, K.M. / Panda, S.P. / Xia, C. / Kim, J.J. / Moutinho, D. / Kranendonk, M. / Auchus, R.J. / Lafer, E.M. / Ghosh, D. / Martasek, P. ...McCammon, K.M. / Panda, S.P. / Xia, C. / Kim, J.J. / Moutinho, D. / Kranendonk, M. / Auchus, R.J. / Lafer, E.M. / Ghosh, D. / Martasek, P. / Kar, R. / Masters, B.S. / Roman, L.J. |
External links | J. Biol. Chem. / PubMed:27496950 |
| Methods | X-ray diffraction |
| Resolution | 2.2 - 2.3 Å |
| Structure data | ![]() PDB-5emn: ![]() PDB-5fa6: |
| Chemicals | ![]() ChemComp-FMN: ![]() ChemComp-FAD: ![]() ChemComp-NAP: ![]() ChemComp-HOH: |
| Source |
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Keywords | OXIDOREDUCTASE / human CYPOR / ABS-like Phenotype / FLAVOPROTEIN / CYTOCHROME P450 REDUCTASE / CYPOR |
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homo sapiens (human)
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