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TitleStructure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease-related H109R variant.
Journal, issue, pagesFebs J., Vol. 283, Page 3587-3603, Year 2016
Publish dateMay 25, 2016 (structure data deposition date)
AuthorsAugustin, P. / Hromic, A. / Pavkov-Keller, T. / Gruber, K. / Macheroux, P.
External linksFebs J. / PubMed:27486859
MethodsX-ray diffraction
Resolution3.09 Å
Structure data

PDB-5l46:
Crystal structure of human dimethylglycine-dehydrogenase
Method: X-RAY DIFFRACTION / Resolution: 3.09 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / electron transfer / covalent flavinylation / one-carbon metabolism

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