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TitleDeciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.
Journal, issue, pagesJ. Biol. Chem., Vol. 291, Page 20353-20371, Year 2016
Publish dateMar 12, 2016 (structure data deposition date)
AuthorsAmin, E. / Jaiswal, M. / Derewenda, U. / Reis, K. / Nouri, K. / Koessmeier, K.T. / Aspenstrom, P. / Somlyo, A.V. / Dvorsky, R. / Ahmadian, M.R.
External linksJ. Biol. Chem. / PubMed:27481945
MethodsX-ray diffraction
Resolution1.72 Å
Structure data

PDB-5irc:
p190A GAP domain complex with RhoA
Method: X-RAY DIFFRACTION / Resolution: 1.72 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-MGF:
TRIFLUOROMAGNESATE

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
  • homo sapiens (human)
KeywordsPROTEIN BINDING / protein-protein complex / transition state / GTPase / GAP domain

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