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TitleGeneration and Characterization of an IgG4 Monomeric Fc Platform.
Journal, issue, pagesPlos One, Vol. 11, Page e0160345-e0160345, Year 2016
Publish dateJan 28, 2016 (structure data deposition date)
AuthorsShan, L. / Colazet, M. / Rosenthal, K.L. / Yu, X.Q. / Bee, J.S. / Ferguson, A. / Damschroder, M.M. / Wu, H. / Dall'Acqua, W.F. / Tsui, P. / Oganesyan, V.
External linksPlos One / PubMed:27479095
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-5hvw:
Monomeric IgG4 Fc
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Biotechnology / antibody engineering / monomeric Fc / monovalent targeting / fusion protein

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