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TitleMore than just recruitment: the X-domain influences catalysis of the first phenolic coupling reaction in A47934 biosynthesis by Cytochrome P450 StaH.
Journal, issue, pagesMol Biosyst, Vol. 12, Page 2992-3004, Year 2016
Publish dateNov 23, 2015 (structure data deposition date)
AuthorsUlrich, V. / Peschke, M. / Brieke, C. / Cryle, M.J.
External linksMol Biosyst / PubMed:27477788
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-5ex6:
Structure of P450 StaH from glycopeptide antibiotic A47934 biosynthesis
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • streptomyces toyocaensis (bacteria)
KeywordsOXIDOREDUCTASE / Cytochrome P450 / monooxygenase / phenolic coupling / glycopeptide antibiotic biosynthesis

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