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TitleStructural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome.
Journal, issue, pagesElife, Vol. 5, Year 2016
Publish dateJan 8, 2016 (structure data deposition date)
AuthorsVan den Bossche, A. / Hardwick, S.W. / Ceyssens, P.J. / Hendrix, H. / Voet, M. / Dendooven, T. / Bandyra, K.J. / De Maeyer, M. / Aertsen, A. / Noben, J.P. ...Van den Bossche, A. / Hardwick, S.W. / Ceyssens, P.J. / Hendrix, H. / Voet, M. / Dendooven, T. / Bandyra, K.J. / De Maeyer, M. / Aertsen, A. / Noben, J.P. / Luisi, B.F. / Lavigne, R.
External linksElife / PubMed:27447594
MethodsX-ray diffraction
Resolution2.2 - 2.75 Å
Structure data

PDB-5ft0:
Crystal structure of gp37(Dip) from bacteriophage phiKZ
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-5ft1:
Crystal structure of gp37(Dip) from bacteriophage phiKZ bound to RNase E of Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

Chemicals

ChemComp-ARG:
ARGININE

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

Source
  • pseudomonas phage phikz (virus)
  • pseudomonas aeruginosa (bacteria)
KeywordsHYDROLASE INHIBITOR / GP37 / DIP / PHIKZ / BACTERIOPHAGE / RNASE E / RIBONUCLEASE INHIBITOR / RNA DEGRADOSOME / HYDROLASE/INHIBITOR / HYDROLASE-INHIBITOR COMPLEX / PSEUDOMONAS AERUGINOSA

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