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Structure paper

TitleNovel thidiazuron-derived inhibitors of cytokinin oxidase/dehydrogenase.
Journal, issue, pagesPlant Mol. Biol., Vol. 92, Page 235-248, Year 2016
Publish dateJan 16, 2016 (structure data deposition date)
AuthorsNisler, J. / Kopecny, D. / Koncitikova, R. / Zatloukal, M. / Bazgier, V. / Berka, K. / Zalabak, D. / Briozzo, P. / Strnad, M. / Spichal, L.
External linksPlant Mol. Biol. / PubMed:27422623
MethodsX-ray diffraction
Resolution2 - 2.05 Å
Structure data

PDB-5hmr:
Crystal structure of maize cytokinin oxidase/dehydrogenase 4 (ZmCKO4) in complex with phenylurea inhibitor 3FMTDZ
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-5hqx:
Crystal structure of maize cytokinin oxidase/dehydrogenase 4 (ZmCKO4) in complex with phenylurea inhibitor HETDZ
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-FDZ:
1-(1,2,3-thiadiazol-5-yl)-3-[3-(trifluoromethoxy)phenyl]urea

ChemComp-HOH:
WATER

ChemComp-EDZ:
1-[2-(2-hydroxyethyl)phenyl]-3-(1,2,3-thiadiazol-5-yl)urea

Source
  • zea mays (maize)
KeywordsOXIDOREDUCTASE / flavoenzyme / cytokinin degradation / oxidase/dehydrogenase / Rossmann fold

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