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-Structure paper
Title | Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment-Based Drug Design Facilitated by Dynamic Combinatorial Chemistry. |
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Journal, issue, pages | Angew. Chem. Int. Ed. Engl., Vol. 55, Page 9422-9426, Year 2016 |
Publish date | Jan 4, 2016 (structure data deposition date) |
Authors | Mondal, M. / Radeva, N. / Fanlo-Virgos, H. / Otto, S. / Klebe, G. / Hirsch, A.K. |
External links | Angew. Chem. Int. Ed. Engl. / PubMed:27400756 |
Methods | X-ray diffraction |
Resolution | 1.36 Å |
Structure data | PDB-5hct: |
Chemicals | ChemComp-DMS: ChemComp-GOL: ChemComp-ACT: ChemComp-61P: ChemComp-EDO: ChemComp-PG4: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / inhibition |