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TitleCacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues.
Journal, issue, pagesCell Death Differ., Vol. 23, Page 1717-1726, Year 2016
Publish dateFeb 22, 2016 (structure data deposition date)
AuthorsSeaman, J.E. / Julien, O. / Lee, P.S. / Rettenmaier, T.J. / Thomsen, N.D. / Wells, J.A.
External linksCell Death Differ. / PubMed:27367566
MethodsX-ray diffraction
Resolution2.65 - 2.7 Å
Structure data

PDB-5ic4:
Crystal structure of caspase-3 DEVE peptide complex
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-5ic6:
Crystal structure of caspase-7 DEVE peptide complex
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / apoptosis / HYDROLASE-HYDROLASE INHIBITOR complex

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