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Structure paper

TitleLoop Electrostatics Asymmetry Modulates the Preexisting Conformational Equilibrium in Thrombin.
Journal, issue, pagesBiochemistry, Vol. 55, Page 3984-3994, Year 2016
Publish dateApr 17, 2016 (structure data deposition date)
AuthorsPozzi, N. / Zerbetto, M. / Acquasaliente, L. / Tescari, S. / Frezzato, D. / Polimeno, A. / Gohara, D.W. / Di Cera, E. / De Filippis, V.
External linksBiochemistry / PubMed:27347732
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-5jdu:
Crystal structure for human thrombin mutant D189A
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Serine protease / Coagulation / conformational equilibrium

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