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-Structure paper
Title | Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML) |
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Journal, issue, pages | Oncotarget, Vol. 7, Page 45562-45574, Year 2016 |
Publish date | Jan 27, 2016 (structure data deposition date) |
![]() | Liu, F. / Wang, B. / Wang, Q. / Qi, Z. / Chen, C. / Kong, L.L. / Chen, J.Y. / Liu, X. / Wang, A. / Hu, C. ...Liu, F. / Wang, B. / Wang, Q. / Qi, Z. / Chen, C. / Kong, L.L. / Chen, J.Y. / Liu, X. / Wang, A. / Hu, C. / Wang, W. / Wang, H. / Wu, F. / Ruan, Y. / Qi, S. / Liu, J. / Zou, F. / Hu, Z. / Wang, L. / Zhang, S. / Yun, C.H. / Zhai, Z. / Liu, Q. |
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Methods | X-ray diffraction |
Resolution | 1.529 Å |
Structure data | ![]() PDB-5hu9: |
Chemicals | ![]() ChemComp-66K: ![]() ChemComp-EDO: ![]() ChemComp-CL: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / Abl / BCR-Abl / CHMFL-074 / TRANSFERASE-TRANSFERASE INHIBITOR complex |