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TitleImpact of Deuteration on the Assembly Kinetics of Transthyretin Monitored by Native Mass Spectrometry and Implications for Amyloidoses.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 55, Page 9292-9296, Year 2016
Publish dateJul 17, 2015 (structure data deposition date)
AuthorsYee, A.W. / Moulin, M. / Breteau, N. / Haertlein, M. / Mitchell, E.P. / Cooper, J.B. / Boeri Erba, E. / Forsyth, V.T.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:27311939
MethodsX-ray diffraction
Resolution1.3 - 1.42 Å
Structure data

PDB-5cn3:
X-ray structure of wild-type TTR at 1.30A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-5cnh:
X-ray structure of perdeuterated wild-type TTR at 1.42A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.42 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / TTR / ATTR / prealbumin

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