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Structure paper

TitleStructural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3
Journal, issue, pagesJ. Biol. Chem., Vol. 291, Page 16709-16719, Year 2016
Publish dateApr 15, 2016 (structure data deposition date)
AuthorsBao, H. / Li, F. / Wang, C. / Wang, N. / Jiang, Y. / Tang, Y. / Wu, J. / Shi, Y.
External linksJ. Biol. Chem. / PubMed:27311713
MethodsX-ray diffraction
Resolution2.1 - 2.3 Å
Structure data

PDB-5jcp:
RhoGAP domain of ARAP3 in complex with RhoA in the transition state
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-5jd0:
crystal structure of ARAP3 RhoGAP domain
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-ALF:
TETRAFLUOROALUMINATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsSIGNALING PROTEIN / HYDROLASE / RhoA / RhoGAP / ARAP3

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