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-Structure paper
Title | Discovery and Sar of Novel 2,3-Dihydroimidazo(1,2-C)Quinazoline Pi3K Inhibitors: Identification of Copanlisib (Bay 80-6946) |
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Journal, issue, pages | Chemmedchem, Vol. 11, Page 1517-, Year 2016 |
Publish date | Apr 11, 2016 (structure data deposition date) |
Authors | Schaefer, M. / Scott, W.J. / Hentemann, M.F. / Rowley, R.B. / Bull, C.O. / Jenkins, S. / Bullion, A.M. / Johnson, J. / Redman, A. / Robbins, A.H. ...Schaefer, M. / Scott, W.J. / Hentemann, M.F. / Rowley, R.B. / Bull, C.O. / Jenkins, S. / Bullion, A.M. / Johnson, J. / Redman, A. / Robbins, A.H. / Esler, W. / Fracasso, R.P. / Garrison, T. / Hamilton, M. / Michels, M. / Wood, J.E. / Wilkie, D.P. / Xiao, H. / Levy, J. / Liu, N. / Stasik, E. / Brands, M. / Lefranc, J. |
External links | Chemmedchem / PubMed:27310202 |
Methods | X-ray diffraction |
Resolution | 2.68 Å |
Structure data | PDB-5g2n: |
Chemicals | ChemComp-6E2: ChemComp-SO4: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE |