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TitleComparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases.
Journal, issue, pagesPlos Pathog., Vol. 12, Page e1005636-e1005636, Year 2016
Publish dateMar 25, 2016 (structure data deposition date)
AuthorsReguera, J. / Gerlach, P. / Rosenthal, M. / Gaudon, S. / Coscia, F. / Gunther, S. / Cusack, S.
External linksPlos Pathog. / PubMed:27304209
MethodsX-ray diffraction
Resolution1.09 - 2.36 Å
Structure data

PDB-5ize:
Hantaan virus L protein cap-snatching endonuclease
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-5izh:
Lassa virus L protein cap-snatching endonuclease. apo form
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-5j1n:
Lassa virus L protein cap-snatching endonuclease. Bound to one manganese ion
Method: X-RAY DIFFRACTION / Resolution: 1.09 Å

PDB-5j1p:
Lassa virus L protein cap-snatching endonuclease. Bound to two manganese ions
Method: X-RAY DIFFRACTION / Resolution: 2.36 Å

Chemicals

ChemComp-MN3:
MANGANESE (III) ION

ChemComp-HOH:
WATER

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

Source
  • hantaan virus
  • lassa mammarenavirus
KeywordsTRANSFERASE / In complex with manganese metal ions / cap-snatching nuclease Lassa transcription

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