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TitleDevelopmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8.
Journal, issue, pagesPlos One, Vol. 11, Page e0157409-e0157409, Year 2016
Publish dateMay 1, 2016 (structure data deposition date)
AuthorsSoto, C. / Ofek, G. / Joyce, M.G. / Zhang, B. / McKee, K. / Longo, N.S. / Yang, Y. / Huang, J. / Parks, R. / Eudailey, J. ...Soto, C. / Ofek, G. / Joyce, M.G. / Zhang, B. / McKee, K. / Longo, N.S. / Yang, Y. / Huang, J. / Parks, R. / Eudailey, J. / Lloyd, K.E. / Alam, S.M. / Haynes, B.F. / Mullikin, J.C. / Connors, M. / Mascola, J.R. / Shapiro, L. / Kwong, P.D.
External linksPlos One / PubMed:27299673
MethodsX-ray diffraction
Resolution1.601 - 3.041 Å
Structure data

PDB-5jny:
Crystal Structure of 10E8 Fab
Method: X-RAY DIFFRACTION / Resolution: 3.041 Å

PDB-5jo5:
Crystal structure of 10E8 gHV-gLV antigen-binding fragment.
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-5jr1:
Crystal structure of 10E8 gHV-matureL antigen-binding fragment.
Method: X-RAY DIFFRACTION / Resolution: 1.601 Å

Chemicals

ChemComp-IPA:
ISOPROPYL ALCOHOL

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / MPER / HIV / antibody / neutralizing / HIV-1 / Antibody development

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