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Structure paper

TitleStructural basis of adhesive binding by desmocollins and desmogleins.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 113, Page 7160-7165, Year 2016
Publish dateNov 13, 2015 (structure data deposition date)
AuthorsHarrison, O.J. / Brasch, J. / Lasso, G. / Katsamba, P.S. / Ahlsen, G. / Honig, B. / Shapiro, L.
External linksProc. Natl. Acad. Sci. USA / PubMed:27298358
MethodsX-ray diffraction
Resolution2.7 - 3.29 Å
Structure data

PDB-5eqx:
Crystal structure of human Desmoglein-3 ectodomain
Method: X-RAY DIFFRACTION / Resolution: 3.05 Å

PDB-5erd:
Crystal structure of human Desmoglein-2 ectodomain
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-5erp:
Crystal structure of human Desmocollin-2 ectodomain fragment EC2-5
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-5iry:
Crystal structure of human Desmocollin-1 ectodomain
Method: X-RAY DIFFRACTION / Resolution: 3.095 Å

PDB-5j5j:
Crystal structure of a chimera of human Desmocollin-2 EC1 and human Desmoglein-2 EC2-EC5
Method: X-RAY DIFFRACTION / Resolution: 3.29 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CA:
Unknown entry

ChemComp-MAN:
alpha-D-mannopyranose

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-SO4:
SULFATE ION

ChemComp-CL:
Unknown entry

Source
  • homo sapiens (human)
KeywordsCELL ADHESION / extracellular cadherin domain / cell surface / desmosome

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