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TitleEffect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry.
Journal, issue, pagesBiophys. Chem., Vol. 216, Page 1-8, Year 2016
Publish dateMar 18, 2016 (structure data deposition date)
AuthorsShah, M.B. / Jang, H.H. / Wilderman, P.R. / Lee, D. / Li, S. / Zhang, Q. / Stout, C.D. / Halpert, J.R.
External linksBiophys. Chem. / PubMed:27280734
MethodsX-ray diffraction
Resolution2.34 - 2.73 Å
Structure data

PDB-5iut:
STRUCTURE OF P450 2B4 F202W MUTANT
Method: X-RAY DIFFRACTION / Resolution: 2.34 Å

PDB-5iuz:
STRUCTURE OF P450 2B4 F202W MUTANT (CYMAL-5)
Method: X-RAY DIFFRACTION / Resolution: 2.73 Å

Chemicals

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-32M:
3,6,9,12,15,18-hexaoxahexacosan-1-ol

ChemComp-HOH:
WATER

ChemComp-CM5:
5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE / detergent*YM

Source
  • oryctolagus cuniculus (rabbit)
KeywordsOXIDOREDUCTASE / CYTOCHROME P450 2B4 / MONOOXYGENASE / MEMBRANE PROTEIN

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