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TitleG-quadruplex RNA binding and recognition by the lysine-specific histone demethylase-1 enzyme.
Journal, issue, pagesRNA, Vol. 22, Page 1250-1260, Year 2016
Publish dateDec 16, 2014 (structure data deposition date)
AuthorsHirschi, A. / Martin, W.J. / Luka, Z. / Loukachevitch, L.V. / Reiter, N.J.
External linksRNA / PubMed:27277658
MethodsX-ray diffraction
Resolution2.803 Å
Structure data

PDB-4xbf:
Structure of LSD1:CoREST in complex with ssRNA
Method: X-RAY DIFFRACTION / Resolution: 2.803 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOxidoreductase/Transcription/RNA / LSD1 / lysine specific demethylase / demethylase / demethylation / RNA / CoREST / REST Co-repressor 1 / amine oxidase / coiled-coil / SWIRM / chromatin remodelling enzyme / epigenetics / histone modifying enzyme / non-coding RNA / ncRNA / KDM1A / Oxidoreductase-Transcription-RNA complex

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