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Structure paper

TitleMolecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma.
Journal, issue, pagesJ. Biol. Chem., Vol. 291, Page 16699-16708, Year 2016
Publish dateNov 26, 2015 (structure data deposition date)
AuthorsMaisonneuve, P. / Caillet-Saguy, C. / Vaney, M.C. / Bibi-Zainab, E. / Sawyer, K. / Raynal, B. / Haouz, A. / Delepierre, M. / Lafon, M. / Cordier, F. / Wolff, N.
External linksJ. Biol. Chem. / PubMed:27246854
MethodsX-ray diffraction
Resolution2.09 - 2.35 Å
Structure data

PDB-5eyz:
CRYSTAL STRUCTURE OF THE PTPN4 PDZ DOMAIN COMPLEXED WITH THE TAILORED PEPTIDE CYTO8-RETEV
Method: X-RAY DIFFRACTION / Resolution: 2.09 Å

PDB-5ez0:
CRYSTAL STRUCTURE OF THE PTPN4 PDZ DOMAIN COMPLEXED WITH THE PDZ BINDING MOTIF OF THE MITOGEN ACTIVATED PROTEIN KINASE P38GAMMA.
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsAPOPTOSIS / CELL DEATH / GLIOBLASTOMA / MULTIPROTEIN COMPLEXES / PDZ DOMAINS / PEPTIDES DESIGN / PROTEIN BINDING / NON-RECEPTOR TYPE 4 / PTPN4 / RABIES VIRUS / PDZ BINDING MOTIF / P38GAMMA / MITOGEN ACTIVATED PROTEIN KINASE

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