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TitleMolecular Mechanism of Z alpha 1-Antitrypsin Deficiency
Journal, issue, pagesJ. Biol. Chem., Vol. 291, Page 15674-15686, Year 2016
Publish dateMar 8, 2016 (structure data deposition date)
AuthorsHuang, X. / Zheng, Y. / Zhang, F. / Wei, Z. / Wang, Y. / Carrell, R.W. / Read, R.J. / Chen, G.Q. / Zhou, A.
External linksJ. Biol. Chem. / PubMed:27246852
MethodsX-ray diffraction
Resolution3.34 Å
Structure data

PDB-5io1:
CRYSTAL STRUCTURE OF RECOMBINANT HUMAN Z ALPHA-1-ANTITRYPSIN
Method: X-RAY DIFFRACTION / Resolution: 3.34 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE INHIBITOR / SERPINS / ACUTE PHASE / ALTERNATIVE SPLICING / BLOOD COAGULATION / DISEASE MUTATION / GLYCOPROTEIN / HYDROLASE / POLYMORPHISM / PROTEASE / PROTEASE INHIBITOR / SECRETED / SERINE PROTEASE INHIBITOR

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