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-Structure paper
Title | Structural determinant for inducing RORgamma specific inverse agonism triggered by a synthetic benzoxazinone ligand. |
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Journal, issue, pages | Bmc Struct. Biol., Vol. 16, Page 7-7, Year 2016 |
Publish date | Mar 23, 2016 (structure data deposition date) |
![]() | Marcotte, D.J. / Liu, Y. / Little, K. / Jones, J.H. / Powell, N.A. / Wildes, C.P. / Silvian, L.F. / Chodaparambil, J.V. |
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Methods | X-ray diffraction |
Resolution | 2.35 - 2.635 Å |
Structure data | ![]() PDB-5ixk: ![]() PDB-5iz0: |
Chemicals | ![]() ChemComp-6EW: ![]() ChemComp-HOH: ![]() ChemComp-6F1: ![]() ChemComp-CL: |
Source |
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![]() | IMMUNE SYSTEM / RORgamma / Nuclear hormone receptor / Inverse agonist / AF2 helix / Agonist |