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| Title | Structural and Functional Analysis of the Allosteric Inhibition of IRE1 alpha with ATP-Competitive Ligands. |
|---|---|
| Journal, issue, pages | Acs Chem. Biol., Vol. 11, Page 2195-2205, Year 2016 |
| Publish date | Jan 8, 2016 (structure data deposition date) |
Authors | Feldman, H.C. / Tong, M. / Wang, L. / Meza-Acevedo, R. / Gobillot, T.A. / Lebedev, I. / Gliedt, M.J. / Hari, S.B. / Mitra, A.K. / Backes, B.J. ...Feldman, H.C. / Tong, M. / Wang, L. / Meza-Acevedo, R. / Gobillot, T.A. / Lebedev, I. / Gliedt, M.J. / Hari, S.B. / Mitra, A.K. / Backes, B.J. / Papa, F.R. / Seeliger, M.A. / Maly, D.J. |
External links | Acs Chem. Biol. / PubMed:27227314 |
| Methods | X-ray diffraction |
| Resolution | 2.584 Å |
| Structure data | ![]() PDB-5hgi: |
| Chemicals | ![]() ChemComp-CS: ![]() ChemComp-NA: ![]() ChemComp-GOL: ![]() ChemComp-DTT: ![]() ChemComp-BME: ![]() ChemComp-CL: ![]() ChemComp-HOH: |
| Source |
|
Keywords | Transferase/Oxidoreductase / Ser/Thr Protein kinase / RNase / Transferase-Oxidoreductase complex |
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