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Structure paper

TitlePhysiological Restraint of Bak by Bcl-Xl is Essential for Cell Survival.
Journal, issue, pagesGenes Dev., Vol. 30, Page 1240-, Year 2016
Publish dateNov 6, 2015 (structure data deposition date)
AuthorsLee, E.F. / Grabow, S. / Chappaz, S. / Dewson, G. / Hockings, C. / Kluck, R.M. / Gray, D.H. / Witkowski, M.T. / Evangelista, M. / Pettikiriarachchi, A. ...Lee, E.F. / Grabow, S. / Chappaz, S. / Dewson, G. / Hockings, C. / Kluck, R.M. / Gray, D.H. / Witkowski, M.T. / Evangelista, M. / Pettikiriarachchi, A. / Bouillet, P. / Lane, R.M. / Czabotar, P.E. / Colman, P.M. / Smith, B.J. / Kile, B.T. / Fairlie, W.D.
External linksGenes Dev. / PubMed:27198225
MethodsX-ray diffraction
Resolution1.491 - 2.43 Å
Structure data

PDB-5fmi:
Human Bak Q77L
Method: X-RAY DIFFRACTION / Resolution: 1.491 Å

PDB-5fmj:
Bcl-xL with mouse Bak BH3 Q75L complex
Method: X-RAY DIFFRACTION / Resolution: 2.43 Å

PDB-5fmk:
Bcl-xL with Bak BH3 complex
Method: X-RAY DIFFRACTION / Resolution: 1.731 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsAPOPTOSIS / BAK / BCL-2 FAMILY / BCL-XL / BH3 DOMAIN

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