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TitleStructural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor.
Journal, issue, pagesSci Rep, Vol. 6, Page 26236-26236, Year 2016
Publish dateOct 14, 2015 (structure data deposition date)
AuthorsHennen, S. / Kodra, J.T. / Soroka, V. / Krogh, B.O. / Wu, X. / Kaastrup, P. / Orskov, C. / Ronn, S.G. / Schluckebier, G. / Barbateskovic, S. ...Hennen, S. / Kodra, J.T. / Soroka, V. / Krogh, B.O. / Wu, X. / Kaastrup, P. / Orskov, C. / Ronn, S.G. / Schluckebier, G. / Barbateskovic, S. / Gandhi, P.S. / Reedtz-Runge, S.
External linksSci Rep / PubMed:27196125
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-5e94:
Antibody-bound Glucagon-like Peptide-1 receptor extracellular domain
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / Antibody antagonist GLP-1 receptor / immune system

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