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TitleEarly Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.
Journal, issue, pagesImmunity, Vol. 44, Page 1215-1226, Year 2016
Publish dateJun 11, 2015 (structure data deposition date)
AuthorsMacLeod, D.T. / Choi, N.M. / Briney, B. / Garces, F. / Ver, L.S. / Landais, E. / Murrell, B. / Wrin, T. / Kilembe, W. / Liang, C.H. ...MacLeod, D.T. / Choi, N.M. / Briney, B. / Garces, F. / Ver, L.S. / Landais, E. / Murrell, B. / Wrin, T. / Kilembe, W. / Liang, C.H. / Ramos, A. / Bian, C.B. / Wickramasinghe, L. / Kong, L. / Eren, K. / Wu, C.Y. / Wong, C.H. / Kosakovsky Pond, S.L. / Wilson, I.A. / Burton, D.R. / Poignard, P.
External linksImmunity / PubMed:27192579
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-5bzw:
Crystal Structure of PCDN-27B, an antibody from the PCDN family of HIV-1 antibodies
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / HIV / Antibody / Fab

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