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Structure paper

TitleThe ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix.
Journal, issue, pagesNucleic Acids Res., Vol. 44, Page 6434-6441, Year 2016
Publish dateFeb 22, 2016 (structure data deposition date)
AuthorsRozov, A. / Westhof, E. / Yusupov, M. / Yusupova, G.
External linksNucleic Acids Res. / PubMed:27174928
MethodsX-ray diffraction
Resolution2.96 - 3.13 Å
Structure data

PDB-5ib7:
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet, near-cognate tRNALys with U-G mismatch in the A-site and antibiotic paromomycin
Method: X-RAY DIFFRACTION / Resolution: 2.99 Å

PDB-5ib8:
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and near-cognate tRNALys with U-G mismatch in the A-site
Method: X-RAY DIFFRACTION / Resolution: 3.13 Å

PDB-5ibb:
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAVal in the A-site
Method: X-RAY DIFFRACTION / Resolution: 2.96 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-PAR:
PAROMOMYCIN / Antimicrobial, medication*YM

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-ZN:
Unknown entry

ChemComp-SPE:
THERMINE

ChemComp-HOH:
WATER

Source
  • thermus thermophilus hb8 (bacteria)
  • escherichia coli k-12 (bacteria)
  • escherichia coli (E. coli)
KeywordsTRANSLATION / ribosome / mismatch

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