+Search query
-Structure paper
Title | Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies. |
---|---|
Journal, issue, pages | Oncogene, Vol. 35, Page 6077-6086, Year 2016 |
Publish date | Aug 1, 2015 (structure data deposition date) |
Authors | Bernasconi-Elias, P. / Hu, T. / Jenkins, D. / Firestone, B. / Gans, S. / Kurth, E. / Capodieci, P. / Deplazes-Lauber, J. / Petropoulos, K. / Thiel, P. ...Bernasconi-Elias, P. / Hu, T. / Jenkins, D. / Firestone, B. / Gans, S. / Kurth, E. / Capodieci, P. / Deplazes-Lauber, J. / Petropoulos, K. / Thiel, P. / Ponsel, D. / Hee Choi, S. / LeMotte, P. / London, A. / Goetcshkes, M. / Nolin, E. / Jones, M.D. / Slocum, K. / Kluk, M.J. / Weinstock, D.M. / Christodoulou, A. / Weinberg, O. / Jaehrling, J. / Ettenberg, S.A. / Buckler, A. / Blacklow, S.C. / Aster, J.C. / Fryer, C.J. |
External links | Oncogene / PubMed:27157619 |
Methods | X-ray diffraction |
Resolution | 2.1 - 3.19 Å |
Structure data | PDB-5czv: PDB-5czx: |
Chemicals | ChemComp-CA: ChemComp-NAG: ChemComp-HOH: ChemComp-EDO: ChemComp-CL: |
Source |
|
Keywords | IMMUNE SYSTEM / ANTIBODY / NOTCH3 / ONCOLOGY |